During Thursday's press conference, Kansas City Chiefs QB Patrick Mahomes commented on playing his first game since Super Bowl LIX | @EdEastonJr

For the third consecutive year, the Kansas City Chiefs reached the Super Bowl, aiming to become the first team in NFL history to win three Vince Lombardi trophies in a row. However

The Kansas City Chiefs are set for their first action of the 2025 NFL preseason with an upcoming tilt against the Arizona Cardinals at State Farm Stadium in Glendale, Arizona. Speaking to media members ahead of the upcoming game,

Patrick Mahomes will take the field for the Kansas City Chiefs' preseason opener against the Arizona Cardinals on Saturday, but he won't have one of his top targets.

But openers don’t always go as planned. Last season, when the Chiefs played their preseason opener at Jacksonville, Patrick Mahomes played the first series, leading the Chiefs to a field goal. Backup Carson Wentz entered the game for the second series, in the first quarter. Before halftime, then-third team quarterback Chris Oladokun led a drive.

During Thursday's press conference, Chiefs head coach Andy Reid detailed expectations for Saturday's preseason opener vs. the Cardinals | @EdEastonJr